UBE2K Polyclonal Antibody


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Cat.No.:  EAb-1583
Product Name:  UBE2K Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB; Recommended dilution: WB 1:500 - 1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  E2-25K, HIP2, HYPG, LIG
Scientific Background:  UBE2K (ubiquitin-conjugating enzyme E2K) belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins and can ubiquitinate huntingtin (of Huntigton's Disease). This protein's functions include participation in accumulated formation of expanded polyglutamine proteins and the repression of apoptosis in polyglutamine diseases, participation in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and a role in foam cell formation. Several transcript variants encoding different isoforms have been found for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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