| Cat.No.: | EAb-1495 |
| Product Name: | UHRF1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Applications: | IF, IHC, WB |
| Recommended Dilutions/Conditions: |
WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:50 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95 |
| Scientific Background: | UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0011 | UHRF2 Polyclonal Antibody | Inquiry |
| EAb-0012 | UHRF1 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0044 | Recombinant Human UHRF1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0416 | Recombinant Human UHRF1 | Inquiry |
| PE-0417 | Recombinant Zebrafish UHRF1 | Inquiry |
| Related Gene / Proteins | |||
| UHRF1 | UHRF2 | ||
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