HAT1 Polyclonal Antibody

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Cat.No.:  EAb-1154
Product Name:  HAT1 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  ChIP, IF, IHC, WB
Recommended Dilutions/Conditions:  WB, IHC, IF, ChIP; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, ChIP 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Histidine aminotransferase 1 antibody, Histone acetyltransferase 1 antibody, Histone acetyltransferase type B catalytic subunit antibody, KAT1 antibody, KAT1
Scientific Background:  The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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