Histone H1K25ac (Acetyl H1K25) Polyclonal Antibody

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Cat.No.:  EAb-1076
Product Name:  Histone H1K25ac (Acetyl H1K25) Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications:  ELISA, IHC, WB
Recommended Dilutions/Conditions:  WB: 1:500-1:2000, IHC: 1:100-1:300, ELISA: 1:20000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Monkey
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  H1FOO; H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1
Scientific Background:  May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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