| Cat.No.: | EAb-0960 |
| Product Name: | LSD1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4. |
| Applications: | ELISA, IF, IHC, WB |
| Recommended Dilutions/Conditions: |
ELISA, WB, IHC, IF; Recommended dilution: IHC: 1:20-1:200, IF: 1:50-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | Amine oxidase flavin containing domain 2 antibody, AOF 2 antibody, BHC110 antibody, BRAF35 HDAC complex protein BHC110 antibody, FAD binding protein BRAF35 HDAC complex 110 kDa subunit antibody, Flavin containing amine oxidase domain containing protein 2 antibody, KDM 1 antibody, KIAA0601 antibody, LSD 1 antibody, Lysine (K) specific demethylase 1A antibody, Lysine specific histone demethylase 1 antibody |
| Scientific Background: | LSD1 is a nuclear homolog of amine oxidases and functions as a histone demethylaseand transcriptional corepressor. LSD1specifically demethylates histone H3 lysine 4,which is linked to active transcription. LSD1 is highly conserved between organismsranging from the fission yeast saccharomyces pombe to humans. LSD1 associates withother histone-modifying enzymes such as histone deacetylases and methyltransferases. In concert with transcription repression, loss of LSD1 function leads to derepression ofgenes regulated by Co-REST, a protein involved in gene silencing and a member ofthe LSD1. |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0062 | Histone Demethylase LSD1 Activity/Inhibition Assay Kit | Inquiry |
| EKIT-0126 | LSD1 Inhibitor Screening Assay Kit | Inquiry |
| EKIT-0160 | LSD1 Demethylase Activity/Inhibition Fluorometric Assay Kit | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0111 | DDP-38003 dihydrochloride | Inquiry |
| BSM-0141 | GSK-LSD1 dihydrochloride | Inquiry |
| Related Gene / Proteins | |||
| LSD1 | LSD2 | LSM2 | LSM3 |
| LSM5 | LSM6 | LSP1 | |
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