| Cat.No.: | EAb-0954 |
| Product Name: | NTMT1 Polyclonal Antibody, Biotin Conjugated |
| Antibody Type: | Polyclonal |
| Conjugate: | Biotin |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | Alpha N-terminal protein methyltransferase 1A, Methyltransferase-like protein 11A, N-terminal RCC1 methyltransferase, X-Pro-Lys N-terminal protein methyltransferase 1A, NTM1A, NTMT1, C9orf32, METTL11A, NRMT, NRMT1, AD-003 |
| Scientific Background: | Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0952 | NTMT1 Polyclonal Antibody, FITC Conjugated | Inquiry |
| EAb-0954 | NTMT1 Polyclonal Antibody, Biotin Conjugated | Inquiry |
| EAb-0955 | NTMT1 Polyclonal Antibody, HRP Conjugated | Inquiry |
| EAb-0956 | NTMT1 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-3441 | Recombinant METTL11B (NTM1B) protein | Inquiry |
| Related Gene / Proteins | |||
| NTM1B | NTMT1 | ||
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