SUV39H1 Monoclonal Antibody


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Cat.No.:  EAb-0921
Product Name:  SUV39H1 Monoclonal Antibody
Antibody Type:  Monoclonal
Conjugate:  Unconjugated
Host:  Mouse
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB; Recommended dilution: WB 1:500 - 1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  H3 K9 HMTase1 antibody, Histone H3 K9 methylation antibody, Histone H3 Lys 9 methylation antibody, Histone H3-K9 methyltransferase 1 antibody, KMT1 A antibody, KMT1A antibody, Lysine N methyltransferase 1A antibody, MG44 antibody, mIS6 antibody, Position-effect variegation 3-9 homolog antibody, Su(var)3 9 homolog 1 antibody, Suppressor of variegation 3 9 homolog 1 (Drosophila) antibody
Scientific Background:  SUV39H1 is a human homologue of the dominant Drosophila PEV modifier Su(var)3-9and is composed of 412 amino acid residues. SUV39H1, as a histone methyltransferase, selectively methylates histone H3 on lysine 9, which generates a binding site for HP1proteins. HP1 proteins are a family of heterochromatic adaptor molecules involved in bothgene silencing and supra-nucleosomal chromatin structure. SUV39H1 plays in importantrole in histone modification and regulation of gene expression.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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