| Cat.No.: | EAb-0914 |
| Product Name: | WDR77 Polyclonal Antibody, HRP Conjugated |
| Antibody Type: | Polyclonal |
| Conjugate: | HRP |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | MEP-50, Androgen receptor cofactor p44, WD repeat-containing protein 77, p44/Mep50, MEP50, WD45, HKMT1069, Nbla10071, WDR77 |
| Scientific Background: | Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0005 | WDR5 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0052 | Recombinant Human WDTC1 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0187 | OICR-9429 | Inquiry |
| BSM-0256 | WDR5 0103 | Inquiry |
| BSM-0335 | MM-102 | Inquiry |
| Related Gene / Proteins | |||
| WDHD1 | WDR4 | WDR5 | WDR77 |
| WDR82 | WDTC1 | ||
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