SMARCA4 Polyclonal Antibody


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Cat.No.:  EAb-0801
Product Name:  SMARCA4 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  IF, WB
Recommended Dilutions/Conditions:  WB, IF; Recommended dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  BAF190, BRG1, FLJ39786, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, hSNF2b
Scientific Background:  SMARCA4 is a member of the SWI/SNF family of proteins that have helicase and ATPase activities and are believed to regulate transcription of certain genes by changing the chromatin structure around those genes. SMARCA4 can bind BRCA1 and can regulate the expression CD44, a tumorigenic protein. Abnormalities in this gene are associated with rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms exist for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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