| Cat.No.: | EAb-0784 |
| Product Name: | Swi2/SNF2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3.. |
| Applications: | IF, IHC, WB |
| Recommended Dilutions/Conditions: |
WB, IHC, IF; Recommended dilution: WB: 1:500 - 1:2000, IHC: 1:50- 1:100, IF: 1:20- 1:50 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | GAM1 antibody, Regulatory protein GAM1 antibody, Regulatory protein SWI2 antibody, RIC1 antibody, SNF2 antibody, SWI/SNF complex component SNF2 antibody, SWI2 antibody, Transcription factor TYE3 antibody, Transcription regulatory protein SNF2 antibody, TYE3 antibody, SMARCA4 Polyclonal Antibody, BAF190, BAF190A, BRG1, CSS4, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b |
| Scientific Background: | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0018 | Swi6 Polyclonal Antibody | Inquiry |
| EAb-0784 | Swi2/SNF2 Polyclonal Antibody | Inquiry |
| EAb-0790 | SNFa/BRM Polyclonal Antibody | Inquiry |
| EAb-1821 | SNAI1 / Snail Monoclonal Antibody | Inquiry |
| EAb-1983 | SND1 Monoclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SNAI1 | Snail | SND1 | SNF2 |
| SNF2L1 | SNF5 | SNFa | SNRP70 |
| SNRPG | Swd2 | Swi2 | Swi6 |
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