CBX2 Polyclonal Antibody, Biotin Conjugated


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Cat.No.:  EAb-0676
Product Name:  CBX2 Polyclonal Antibody, Biotin Conjugated
Product Overview:  Polyclonal Antibody to detect CBX2
Antibody Type:  Polyclonal
Conjugate:  Biotin
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q14781
Alternative Name:  Chromobox protein homolog 2, CBX2
Scientific Background:  Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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