DNMT3A Polyclonal Antibody


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Cat.No.:  EAb-0652
Product Name:  DNMT3A Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applications:  IF, IHC, WB
Recommended Dilutions/Conditions:  WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  DNA (cytosine 5) methyltransferase 3 alpha antibody, DNA (cytosine-5)-methyltransferase 3A antibody, DNA cytosine methyltransferase 3A2 antibody, DNA methyltransferase 3a antibody, DNA methyltransferase HsaIIIA antibody, DNA MTase HsaI antibody, DNA MTase HsaIIIA antibody, DNM3A_HUMAN antibody, DNMT 3a antibody, DNMT antibody, DNMT3A2 antibody, M HsaIIIA antibody, MCMT antibody, Methyl CpG binding domain protein 3a antibody, OTTHUMP00000201149 antibody, DNMT3A2, M.HsaIIIA
Scientific Background:  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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