ALKBH3 Polyclonal Antibody (FITC Conjugated)


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Cat.No.:  EAb-0638
Product Name:  ALKBH3 Polyclonal Antibody (FITC Conjugated)
Antibody Type:  Polyclonal
Conjugate:  FITC
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Alkylated DNA repair protein alkB homolog 3, DEPC-1, Prostate cancer antigen 1, ABH3, DEPC1, ALKBH3
Scientific Background:  Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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