| Cat.No.: | EAb-0635 |
| Product Name: | APOBEC3A Polyclonal Antibody (FITC Conjugated) |
| Antibody Type: | Polyclonal |
| Conjugate: | FITC |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | A3A, APOBEC3A, Phorbolin-1 |
| Scientific Background: | DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0374 | APOBEC3D Polyclonal Antibody | Inquiry |
| EAb-0375 | APOBEC2 Polyclonal Antibody | Inquiry |
| EAb-0393 | APOBEC3G Polyclonal Antibody | Inquiry |
| EAb-0403 | APOBEC3C Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0388 | Human APTX Knockout Cell Line 11bp deletion | Inquiry |
| Related Gene / Proteins | |||
| AP-2 | Ape1 | APOBEC2 | APOBEC3A |
| APOBEC3B | APOBEC3C | APOBEC3D | APOBEC3F |
| APOBEC3G | APOBEC3H | APOBEC4 | APTX |
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