| Cat.No.: | EAb-0489 |
| Product Name: | Dnmt2 Monoclonal Antibody (102B1259.2) |
| Antibody Type: | Monoclonal |
| Clone Designation: | 102B1259.2 |
| Immunogen: | This antibody was raised against synthetic peptides corresponding to mouse Dnmt2. |
| Host: | Mouse |
| Isotype: | IgG1 Kappa |
| Antibody Target: | TRDMT1 |
| Specificity: | In mouse Dnmt2 transfected cell lysate, a 42 kDa band is oberseved. |
| Purification: | Protein G purified |
| Appearance: | Liquid |
| Formulation: | PBS containing 0.2% gelatin |
| Applications: | WB, Flow, ICC/IF |
| Recommended Dilutions/Conditions: |
Western Blot 1:100-1:2000; Flow Cytometry; Immunocytochemistry/Immunofluorescence Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Zebrafish |
| Storage: | -20°C |
| Storage Buffer: | 0.05% Sodium Azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | DMNT2; DNA (cytosine-5-)-methyltransferase 2; DNA (cytosine-5)-methyltransferase-like protein 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNMT2; EC 2.1.1; EC 2.1.1.29; M.HsaIIP; MHSAIIP; PUMET; RNMT1; tRNA (cytosine-5-)-methyltransferase; tRNA aspartic acid methyltransferase 1 |
| Scientific Background: | Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0107 | Recombinant Human TRIM68 293 Cell Lysate | Inquiry |
| EL-0109 | Recombinant Human TRIP4 Lysate | Inquiry |
| EL-0115 | Recombinant Human TRIM24 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| TRA2A | TRAF4 | TRAF5 | TRAF6 |
| TRAK2 | TRBP | TRDMT1 | TREX1 |
| TRF2 | TRIM11 | TRIM13 | TRIM16 |
| TRIM17 | TRIM2 | TRIM21 | trim24 |
| TRIM26 | TRIM28 | TRIM3 | TRIM33 More > |
| TRIM34 | TRIM35 | TRIM36 | TRIM37 |
| TRIM38 | TRIM39 | TRIM4 | TRIM5 |
| TRIM55 | TRIM6 | TRIM63 | TRIM66 |
| TRIM68 | TRIM8 | TRIM9 | TRIML1 |
| TRIP4 | Tristetraprolin | TRIT1 | TrkA |
| TRMT2A | TRMT44 | TRMT5 | TRMT6 |
| TROVE2 | TRUB2 | TRX1 | TRβ1 |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
