Cat.No.: | EAb-0417 |
Product Name: | YBX1 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | A synthetic peptide of human YBX1 |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Affinity purification |
Appearance: | Liquid |
Applications: | WB, IHC |
Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human, Mouse, Rat |
Storage: | -20°C |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | P67809 |
Alternative Name: | BP 8,CBF-A,CCAAT binding transcription factor I subunit A,CCAAT-binding transcription factor I subunit A,CSDA2,CSDB,DBPB,DNA binding protein B,DNA-binding protein B,EFI-A,Enhancer factor I subunit A,MDR NF1,MGC104858,MGC110976,MGC117250,NSEP 1,NSEP1,Nuclease sensitive element binding protein 1,Nuclease-sensitive element-binding protein 1,p50,Q15905,Y-box binding protein 1,Y-box transcription factor,Y-box-binding protein 1,YB 1,YB-1,YBOX1,YBX 1,ybx1 |
Scientific Background: | This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. |
Product Types | ||
◆ Synthetic Peptides | ||
SP-0175 | Human YB1 peptide | Inquiry |
◆ Antibodies | ||
EAb-0417 | YBX1 Polyclonal Antibody | Inquiry |
◆ Proteins & Enzymes | ||
PE-2456 | Recombinant Human YB1 protein | Inquiry |
PE-2478 | Recombinant Human MSY2/YBOX2/YBX2 protein | Inquiry |
Related Gene / Proteins | |||
YB1 | YBOX2 | YBX1 | YBX2 |
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