EZH2 Polyclonal Antibody


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  • Target Information
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Cat.No.:  EAb-0414
Product Name:  EZH2 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  KLH conjugated Synthetic peptide corresponding to Mouse EZH2
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB: 1:500-1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Storage Buffer:  PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q15910, Q61188
Alternative Name:  EZH2; ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2; histone-lysine N-methyltransferase EZH2
Scientific Background:  EZH2 (enhancer of zeste homologue 2,also known as KMT6) is a member of Polycomb group (PcG) family and encodes a histone methyl transferase that has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing. EZH2 is important for cell proliferation and inhibition of cell differentiation,and is implicated in cancer progression. Overexpression of EZH2 is a marker of advanced and metastatic disease in many solid tumors,including prostate and breast cancer.
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Related Gene / Proteins
ezh1 EZH2

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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