| Cat.No.: | EAb-0406 |
| Product Name: | NEDD4L Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human NEDD4L |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | IHC, ELISA |
| Recommended Dilutions/Conditions: |
IHC 1:50-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q96PU5 |
| Alternative Name: | E3 ubiquitin protein ligase NEDD4 like protein,E3 ubiquitin-protein ligase NEDD4-like,KIAA0439,NED4L,NEDD4 2,NEDD4 2c,Nedd4-2,NEDD4-2a,NEDD4.2,NEDD4b,NEDD4L,NEDD4La,NEDD4Lb,NEDD4Lc,NEDD4Ld,NEDD4Le,NEDD4Lf,NEDD4Lg,NEDD4Lh,NEDL3,Neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase,Neural precursor cell expressed,developmentally down regulated 4 like,RSP5,Ubiquitin protein ligase Rsp5 |
| Scientific Background: | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0406 | NEDD4L Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0444 | Human NEIL1 Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2399 | Recombinant Human NEDD4-2 protein | Inquiry |
| PE-2400 | Recombinant Human NEDD4-2 protein | Inquiry |
| Related Gene / Proteins | |||
| NEDD4 | NEDD4L | NEIL1 | |
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