Cat.No.: | EAb-0394 |
Product Name: | PRMT7 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | Recombinant protein of human PRMT7 |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Affinity purification |
Appearance: | Liquid |
Applications: | WB, ELISA |
Recommended Dilutions/Conditions: |
WB: 1:500-1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human |
Storage: | -20°C |
Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Q9NVM4 |
Alternative Name: | [Myelin basic protein]-arginine N-methyltransferase PRMT7,ANM7,FLJ10640,Histone-arginine N-methyltransferase PRMT7,KIAA1933,Myelin basic protein arginine N methyltransferase,OTTHUMP00000174863,PRMT7,Protein arginine methyltransferase 7,Protein arginine N-methyltransferase 7 |
Scientific Background: | Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
BSM-0047 | SGC707 | Inquiry |
◆ Antibodies | ||
EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
Pr-SET7 | PRC1 | PRC2 | PRDM1 |
PRDM10 | PRDM11 | PRDM12 | PRDM13 |
PRDM14 | PRDM15 | PRDM16 | PRDM17 |
PRDM2 | PRDM3 | PRDM4 | PRDM5 |
PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
PREP1 | PRIM2 | PRKAA2 | PRKCA |
PRKCB | PRKCE | PRKDC | PRKRIP1 |
PRMT | prmt1 | PRMT2 | PRMT3 |
PRMT5 | prmt6 | PRMT7 | PRMT8 |
PRMT9 | Progerin | Protamine 2 | Prox1 |
PRPF31 | PRPF40A | PRSS12 | PRSS55 |
PRTFDC1 |
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