PRMT7 Polyclonal Antibody


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Cat.No.:  EAb-0394
Product Name:  PRMT7 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant protein of human PRMT7
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB, ELISA
Recommended Dilutions/Conditions:  WB: 1:500-1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Storage Buffer:  PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9NVM4
Alternative Name:  [Myelin basic protein]-arginine N-methyltransferase PRMT7,ANM7,FLJ10640,Histone-arginine N-methyltransferase PRMT7,KIAA1933,Myelin basic protein arginine N methyltransferase,OTTHUMP00000174863,PRMT7,Protein arginine methyltransferase 7,Protein arginine N-methyltransferase 7
Scientific Background:  Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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