SUV39H1 Polyclonal Antibody


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Cat.No.:  EAb-0389
Product Name:  SUV39H1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant Protein of human SUV39H1
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Storage Buffer:  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  O43463
Alternative Name:  H3 K9 HMTase1,H3-K9-HMTase 1,Histone H3-K9 methyltransferase 1,Histone H3-K9 methyltransferase1,Histone lysine N methyltransferase, H3 lysine 9 specific 1,Histone-lysine N-methyltransferase SUV39H1,KMT1 A,KMT1A,Lysine N methyltransferase 1A,Lysine N-methyltransferase 1A,MG44,mIS6,Position-effect variegation 3-9 homolog,Su(var)3 9 homolog 1,Su(var)3-9 homolog 1,Suppressor of variegation 3 9 homolog 1 (Drosophila),Suppressor of variegation 3-9 homolog 1,SUV39 H1,SUV39H,SUV39H1,SUV91
Scientific Background:  This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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