| Cat.No.: | EAb-0380 |
| Product Name: | MYSM1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide of human MYSM1 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IHC, ELISA |
| Recommended Dilutions/Conditions: |
WB: 1:500-1:2000; IHC: 1:50-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q5VVJ2 |
| Alternative Name: | 2A-DUB,2ADUB,Histone H2A deubiquitinase,Histone H2A deubiquitinase MYSM1,KIAA1915,Myb like SWIRM and MPN domains 1,Myb like,SWIRM and MPN domain containing protein,Myb like,SWIRM and MPN domains 1,Myb-like,Myb-like,SWIRM and MPN domains 1,MYSM 1,mysm1,MYSM1 Myb-like,SWIRM and MPN domains 1,MYSM1,RP4-592A1.1,SWIRM and MPN domain-containing protein 1 |
| Scientific Background: | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0174 | Human KAT8 / MYST1 / MOF peptide | Inquiry |
| ◆ Antibodies | ||
| EAb-0184 | MYCBP Polyclonal Antibody | Inquiry |
| EAb-0204 | c-Myb Polyclonal Antibody | Inquiry |
| EAb-0380 | MYSM1 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0344 | Human MYSM1 Knockout Cell Line 7bp deletion | Inquiry |
| Related Gene / Proteins | |||
| MYB | Myc | MYCBP | Myf-5 |
| Myocilin | MyoD | MYSM1 | MYST1 |
| MYST3 | Myt1 | ||
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