| Cat.No.: | EAb-0378 |
| Product Name: | SETD2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human SETD2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB |
| Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9BYW2 |
| Alternative Name: | EC 2.1.1.43,FLJ16420,FLJ22472,FLJ23184,FLJ45883,HBP231,HIF 1,HIF-1,HIF1,HIP-1,Histone lysine N methyltransferase SETD2,Histone-lysine N-methyltransferase SETD2,hSET2,HSPC069,Huntingtin interacting protein 1,Huntingtin interacting protein,Huntingtin interacting protein B,Huntingtin interacting protein HYPB,Huntingtin yeast partner B,Huntingtin-binding protein,231-KD,Huntingtin-interacting protein 1,Huntingtin-interacting protein B,HYPB,KIAA1732,KMT3A,Lysine N methyltransferase 3A,Lysine N-methyltransferase 3A,p231HBP,SET domain containing 2,SET domain-containing protein 2,SET2,SETD2,SETD2 |
| Scientific Background: | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
| EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
| EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
| EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SENP3 | SENP8 | SET | SET1 |
| SET2 | SET7 | SET8 | SET9 |
| SETBP1 | SETD1A | SETD1B | SETD2 |
| SETD3 | SETD5 | SETD6 | SETD7 |
| SETD8 | SETD9 | SetDB1 | SETDB2 More > |
| SETMAR | |||
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