| Cat.No.: | EAb-0352 |
| Product Name: | MECP2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human MECP2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IHC, ELISA |
| Recommended Dilutions/Conditions: |
WB: 1:200-1:1000; IHC: 1:100-1:300 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P51608 |
| Alternative Name: | AUTSX 3,AUTSX3,DKFZp686A24160,Mbd 5,Mbd5,MECP 2,MeCP 2 protein,MeCP-2 protein,Mecp2,MECP2,Methyl CpG binding protein 2 (Rett syndrome),Methyl CpG binding protein 2,Methyl-CpG-binding protein 2,MRX 16,MRX 79,MRX16,MRX79,MRXS 13,MRXS13,MRXSL,PPMX,RS,RTS,RTT,WBP 10,WBP10 |
| Scientific Background: | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0043 | Recombinant Human MECP2 293 Cell Lysate | Inquiry |
| EL-0111 | Recombinant Human MEF2B Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0067 | MeCP2 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0109 | Human MECP2 Knockout Cell Line 1bp insertion | Inquiry |
| CL-0110 | Human MEN1 Knockout Cell Line 1bp insertion | Inquiry |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
