| Cat.No.: | EAb-0337 |
| Product Name: | Histone H1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthesized peptide derived from human Histone H1 around the non-phosphorylation site of Thr17. |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IHC-p, IF, ELISA |
| Recommended Dilutions/Conditions: |
WB: 1:500-1:2000; IHC: 1:100-1:300; IF: 1:200-1:1000; ELISA: 1:20000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P16401, P16402, P10412 |
| Alternative Name: | HIST1H1B,H1F5,Histone H1.5,Histone H1a,Histone H1b,Histone H1s-3,HIST1H1D,H1F3,Histone H1.3,Histone H1c,Histone H1s-2,HIST1H1E,H1F4,Histone H1.4,Histone H1b,Histone H1s-4 |
| Scientific Background: | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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