| Cat.No.: | EAb-0307 |
| Product Name: | DDB2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human DDB2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IF |
| Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000; IF: 1:50 - 1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q92466 |
| Alternative Name: | damage-specific DNA binding protein 2,Damage-specific DNA-binding protein 2,DDB p48 subunit,Ddb2,DDB2,DDBb,DNA damage-binding protein 2,UV-damaged DNA-binding protein 2,UV-DDB 2,Xeroderma pigmentosum group E protei |
| Scientific Background: | This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0055 | Phospho-DDX3X (Thr322) Polyclonal Antibody | Inquiry |
| EAb-0306 | DDX43 Polyclonal Antibody | Inquiry |
| EAb-0307 | DDB2 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0057 | Recombinant Human DDX20 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0178 | Human RIG-I/DDX58 peptide | Inquiry |
| Related Gene / Proteins | |||
| DDB2 | Ddit3 | DDX10 | DDX18 |
| DDX20 | DDX28 | DDX3X | DDX41 |
| DDX42 | DDX43 | DDX49 | DDX50 |
| DDX58 | |||
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