| Cat.No.: | EAb-0305 |
| Product Name: | CBX5 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human CBX5 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IF, IP |
| Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000; IF: 1:50 - 1:200; IP: 1:50 - 1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P45973 |
| Alternative Name: | Antigen p25,CBX5,CBX5,CG8409,Chromobox 5,Chromobox homolog 5 (HP1 alpha homolog,Drosophila),Chromobox homolog 5,Chromobox protein homolog 5,Epididymis luminal protein 25,HEL25,Heterochromatin protein 1 alpha,Heterochromatin protein 1,Heterochromatin protein 1 homolog alpha,HP1 alpha,HP1 alpha homolog,HP1,HP1A,HP1Hs alpha,Su(var)205 |
| Scientific Background: | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0053 | Human CBX5 Knockout Cell Line 2bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0146 | CBX5 Polyclonal Antibody | Inquiry |
| EAb-0148 | CBX3 Polyclonal Antibody | Inquiry |
| EAb-0150 | CBX2 Polyclonal Antibody | Inquiry |
| EAb-0153 | CBFb Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| CBFb | CBX2 | CBX3 | CBX4 |
| CBX5 | CBX6 | CBX7 | CBX8 |
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