| Cat.No.: | EAb-0304 |
| Product Name: | FBL Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human FBL |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IF, IP |
| Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000; IF: 1:50 - 1:200; IP: 1:50 - 1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat, Monkey |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P22087 |
| Alternative Name: | 34 kD nucleolar scleroderma antigen,34 kDa nucleolar scleroderma antigen,Fbl,FBRL,FIB,FIB1,FLRN,Histone-glutamine methyltransferase,Nop1p,RNA U3 small nucleolar interacting protein 1,RNU3IP1,rRNA 2' O methyltransferase fibrillarin,rRNA 2'-O-methyltransferase fibrillarin |
| Scientific Background: | This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0183 | FBXL10 (KDM2B) Chemiluminescent Assay Kit | Inquiry |
| EKIT-0184 | FBXL11 (KDM2A) Homogeneous Assay Kit | Inquiry |
| EKIT-0558 | FBXL10 (KDM2B) Homogeneous Assay Kit | Inquiry |
| ◆ Cell Lines | ||
| CL-0199 | Human FBXO38 Knockout Cell Line | Inquiry |
| ◆ Antibodies | ||
| EAb-0304 | FBL Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| FBL | FBXL10 | FBXL11 | FBXL17 |
| FBXL18 | FBXL2 | FBXO15 | FBXO16 |
| FBXO24 | FBXO25 | FBXO28 | FBXO3 |
| FBXO30 | FBXO38 | FBXO40 | FBXO44 |
| FBXW10 | FBXW12 | FBXW2 | FBXW9 |
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