RBM3 Polyclonal Antibody


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Cat.No.:  EAb-0295
Product Name:  RBM3 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant Human RNA-binding protein 3 protein
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  IHC
Recommended Dilutions/Conditions:  IHC: 1:100-1:400
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Storage Buffer:  PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  P98179
Alternative Name:  2600016C11Rik,IS1 RNPL,MGC105811,MGC118410,Putative RNA binding protein 3,Putative RNA-binding protein 3,Rbm3,RBM3,RNA binding motif (RNP1, RRM) protein 3,RNA binding motif protein 3,RNA-binding motif protein 3,RNA-binding protein 3,RNPL,RP23-27I6.7
Scientific Background:  RBM3, also named as RNPL, is a cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. It reduces the relative abundance of microRNAs, when overexpressed. RBM3 enhances phosphoryaltion of translation initiation factors and active polysome formation. It is up-regulated in human tumors. RBM3 is a potential proto-oncogenic proteins upon overexpression.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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