| Cat.No.: | EAb-0277 |
| Product Name: | BRD4/HUNK1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | synthetic peptide from human Brd4 within the region of amino acids 150-200 |
| Host: | Rabbit |
| Appearance: | Liquid |
| Formulation: | 100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide |
| Applications: | WB |
| Species Reactivity: | Human Brd4, Chimpanzee Brd4, Mouse Brd4, Rat Brd4 |
| Shipping: | Wet ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | O60885 |
| Alternative Name: | Bromodomain containing protein 4 |
| Scientific Background: | BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of the BET protein family. It is a human homolog of mouse mCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminal region with proline and glutamine-rich domains. BRD4 is a chromatin-binding protein whos expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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