| Cat.No.: | EAb-0266 |
| Product Name: | JARID1B/PLU1 (C-Term) Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide from the C-terminal region of human JARID1B/PLU1 |
| Host: | rabbit |
| Appearance: | Liquid |
| Formulation: | Peptide affinity-purified polyclonal antibody |
| Applications: | FC and ICC |
| Species Reactivity: | Human JARID1B/PLU1 |
| Shipping: | Wet ice |
| Storage: | -20°C |
| Storage Buffer: | TBS, pH 7.4 with 50% glycerol, 0.1% BSA and 0.02% sodium azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9UGL1 |
| Alternative Name: | CT31;Jumonji/ARID domain-containing protein 1B;KDM5B;Lysine-specific Demethylase 5B;RBBP2H1 |
| Scientific Background: | Jumonji AT rich interactive domain 1B (JARID1B) nuclear proteins are potential histone demethylases. JARID1B demethylation of Lys-4 of histone H3 plays an important role in breast cancer cell proliferation through BRCA1 repression. JARID1B acts as a transcriptional co-repressor of two developmental transcription factors, PAX-9 and BF1, which are crucial for organogenesis in mouse embryo. JARID1B has also been shown to interact directly with histone deacetylase. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0002 | AT9283 | Inquiry |
| ◆ Cell Lines | ||
| CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| CL-0081 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
| EAb-0080 | JARID1C Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JADE1 | JAK | JAK1 | JAK2 |
| JAK3 | JAKMIP1 | JARID | JARID1 |
| JARID1A | JARID1B | JARID1C | JARID2 |
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