| Cat.No.: | EAb-0250 |
| Product Name: | trimethyl Histone H3 (Lys4) Monoclonal Antibody (Clone RM137) |
| Description: | This antibody reacts to histone H3 trimethylated at lysine 4 (K4me3) and does not detect monomethylated lysine 4 (K4me1), dimethylated lysine 4 (K4me2), or other methylations in histone H3. |
| Antibody Type: | Monoclonal |
| Clone Designation: | RM137 |
| Immunogen: | A trimethyl-peptide corresponding to trimethyl-histone H3 (Lys4) |
| Host: | Rabbit |
| Isotype: | IgG |
| Appearance: | Liquid |
| Formulation: | 100 μg of protein A affinity-purified antibody from an animal origin–free culture supernatant |
| Applications: | ELISA, Multiplex, and WB |
| Species Reactivity: | All species |
| Shipping: | Wet ice |
| Storage: | -20°C |
| Storage Buffer: | 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Histone H3 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription. Methylation at lysine 4 of histone 3 (H3K4) is an evolutionarily conserved modification associated with transcriptionally active chromatin. The SET1/MLL (KMT2) family of methyltransferases is the principal enzyme family responsible for H3K4 methylations. |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0001 | Acetyl Histone H3-K14 Quantification Kit (Colorimetric) | Inquiry |
| EKIT-0002 | Acetyl Histone H3-K14 Quantification Kit (Fluorometric) | Inquiry |
| EKIT-0003 | Acetyl Histone H3-K18 Quantification Kit (Colorimetric) | Inquiry |
| EKIT-0004 | Acetyl Histone H3-K18 Quantification Kit (Fluorometric) | Inquiry |
| EKIT-0005 | Acetyl Histone H3-K23 Quantification Kit (Colorimetric) | Inquiry |
| Related Gene / Proteins | |||
| H3K10 | H3K115 | H3K122 | H3K123 |
| H3K14 | H3K18 | H3K23 | H3K27 |
| H3K36 | H3K37 | H3K4 | H3K5 |
| H3K56 | H3K64 | H3K79 | H3K80 |
| H3K9 | H3R128 | H3R17 | H3R2 More > |
| H3R26 | H3R8 | H3R9 | H3S10 |
| H3S28 | H3S31 | H3S32 | H3T11 |
| H3T118 | H3T3 | H3T32 | H3T41 |
| H3T45 | H3T6 | H3T80 | H3Y41 |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
