| Cat.No.: | EAb-0248 |
| Product Name: | PAD3 Monoclonal Antibody (Clone 4E5) |
| Antibody Type: | Monoclonal |
| Clone Designation: | 4E5 |
| Immunogen: | Full length recombinant PAD3 protein |
| Host: | Mouse |
| Isotype: | IgG1 |
| Appearance: | Liquid |
| Formulation: | 100 µg of Protein G-purified antibody |
| Applications: | ELISA and WB |
| Species Reactivity: | Human |
| Shipping: | Wet ice |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 50% glycerol with 0.02% sodium azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9ULW8 |
| Alternative Name: | PADI3;PDI3;Peptidylarginine Deiminase 3;Protein Arginine Deiminase 3 |
| Scientific Background: | Protein arginine deiminase 3 (PAD3) is a homodimeric guanidine-modifying enzyme belonging to the amidinotransferase superfamily. It is a calcium-dependent enzyme that catalyzes the post-translational modification of target proteins by converting arginine to citrulline. Substrates of PAD3 include filaggrin, trichohyalin, apoptosis-inducing factor (AIF), vimentin, and other proteins. PAD3 is expressed in the epidermis, hair follicles, and keratinocytes. It has a role in shaping and mechanical strengthening of hair, and mutations in PAD3 lead to uncombable hair syndrome. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0059 | PARP Monoclonal Antibody | Inquiry |
| EAb-0061 | PARP Polyclonal Antibody | Inquiry |
| EAb-0062 | PARP (Cleaved) Polyclonal Antibody | Inquiry |
| EAb-0063 | PARP (Cleaved) Polyclonal Antibody | Inquiry |
| EAb-0064 | Paf1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| PABPC1L2A | PABPC5 | PABPN1 | PAD |
| PAD1 | PAD2 | PAD3 | PAD4 |
| PADI1 | PADI2 | PADI3 | PADI4 |
| PADI6 | PAF1 | PAN2 | PAPD1 |
| PAPD4 | PAPD5 | PAPD7 | PAPOLA More > |
| PAPOLB | PARD6A | PARG | PARK2 |
| PARK7 | PARP | PARP1 | PARP10 |
| PARP11 | PARP12 | PARP14 | PARP15 |
| PARP16 | PARP2 | PARP3 | PARP4 |
| PARP6 | PARP7 | PARP8 | PARP9 |
| PAX5 | PAX6 | PAX7 | PAX9 |
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