| Cat.No.: | EAb-0244 |
| Product Name: | TRDMT1/DNMT2 Monoclonal Antibody (1E12) |
| Antibody Type: | Monoclonal |
| Immunogen: | Recombinant full length TRDMT1 (DNMT2) (aa 1-392) fused to a GST tag. |
| Host: | Mouse |
| Isotype: | IgG1λ |
| Purification: | Protein A purified. |
| Appearance: | Liquid |
| Formulation: | In 1x PBS, pH 7.2. |
| Applications: | ELISA, IF, WB |
| Recommended Dilutions/Conditions: |
ELISA (0.25-1µg/ml)Immunofluorescence (5µg/ml)Western Blot (0.5-1µg/ml). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Shipping: | Blue Ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | O14717 |
| Alternative Name: | tRNA (cytosine(38)-C(5))-methyltransferase, PuMet |
| Scientific Background: | In 2006, TRDMT1 enzyme was shown to methylate position 38 in aspartic acid transfer RNA and does not methylate DNA. To reflect this different function, the name for this methyltransferase was changed from DNMT2 to TRDMT1 (tRNA aspartic acid methyltransferase 1) to better reflect its biological function. TRDMT1 is the first RNA cytosine methyltransferase to be identified in a human. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
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