| Cat.No.: | EAb-0239 |
| Product Name: | LSD1/AOF2 Monoclonal Antibody (1B2F2) |
| Antibody Type: | Monoclonal |
| Immunogen: | Recombinant human LSD1 truncated protein. |
| Host: | Mouse |
| Isotype: | IgG1 |
| Purification: | Purified from mouse ascites. Protein G affinity purified. |
| Appearance: | Liquid |
| Formulation: | In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| Applications: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Shipping: | Blue Ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | O60341 |
| Scientific Background: | Lysine-specific demethylase 1 (LSD1, AOF2, BHC110) is a nuclear amine oxidase homolog, and was the first such protein to display definitive activity in epigenetic modulation as a histone demethylase. LSD1 demethylates histone H3 at mono- or di-methylated lysine residues. Depending on associated co-factors, LSD1-mediated demethylation can lead to transcriptional repression or activation. |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0062 | Histone Demethylase LSD1 Activity/Inhibition Assay Kit | Inquiry |
| EKIT-0126 | LSD1 Inhibitor Screening Assay Kit | Inquiry |
| EKIT-0160 | LSD1 Demethylase Activity/Inhibition Fluorometric Assay Kit | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0111 | DDP-38003 dihydrochloride | Inquiry |
| BSM-0141 | GSK-LSD1 dihydrochloride | Inquiry |
| Related Gene / Proteins | |||
| AOF2 | LSD1 | LSD2 | LSM2 |
| LSM3 | LSM5 | LSM6 | LSP1 |
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