| Cat.No.: | EAb-0202 |
| Product Name: | ASF1A Polyclonal Antibody |
| Product Overview: | Polyclonal antibody to detect endogenous levels of ASF1A in human, mouse and rat. |
| Antibody Type: | Polyclonal |
| Immunogen: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ASF1A |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | ASF1A |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Applications: | WB, IF/IC |
| Recommended Dilutions/Conditions: |
WB; 1:500 – 1:2000, IF/IC; 1:50 – 1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | WB: Jurkat, A549, MCF7, mouse lung, rat lung lysate |
| Species Reactivity: | Human, Mouse, Rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9Y294 |
| Alternative Name: | Histone chaperone ASF1A, Anti-silencing function protein 1 homolog A, hAsf1, hAsf1a, CCG1-interacting factor A, CIA, hCIA |
| Scientific Background: | Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0018 | Human ASH1L Knockout Cell Line 53bp deletion | Inquiry |
| CL-0019 | Human ASXL2 Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0162 | Recombinant Human ASH2L 293 Cell Lysate | Inquiry |
| EL-0173 | Recombinant Human ASF1A 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0168 | ASH2 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| ASB10 | ASB11 | ASB13 | ASB6 |
| ASB7 | ASB8 | ASB9 | ASF1 |
| ASH1L | ASH2 | ASXL2 | |
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