| Cat.No.: | EAb-0199 |
| Product Name: | CHRDL1 Monoclonal Antibody (3H1-F6-A10) |
| Product Overview: | Monoclonal antibody to detect endogenous levels of CHRDL1 in human samples |
| Antibody Type: | Monoclonal |
| Immunogen: | Purified recombinant human CHRDL1 protein fragments expressed in E.coli. |
| Host: | Mouse |
| Isotype: | IgG |
| Antibody Target: | CHRDL1 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Applications: | WB, ELISA |
| Recommended Dilutions/Conditions: |
WB: WB 1:500-1:2000, ELISA 1:10000-20000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | WB: Human eye and HeLa cell lysate, IF/ICC: HeLa cells |
| Species Reactivity: | Human |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9BU40 |
| Alternative Name: | Chordin-like protein 1, Neuralin-1, Neurogenesin-1, Ventroptin, NRLN1 |
| Scientific Background: | Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation . May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0147 | Recombinant Human CHAF1A 293 Cell Lysate | Inquiry |
| EL-0167 | Recombinant Human CHAF1B 293 Cell Lysate | Inquiry |
| EL-0211 | Recombinant Human CHD2 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0180 | Mouse Chd7 peptide | Inquiry |
| ◆ Antibodies | ||
| EAb-0199 | CHRDL1 Monoclonal Antibody (3H1-F6-A10) | Inquiry |
| Related Gene / Proteins | |||
| CHAF1A | CHAF1B | CHD1 | CHD2 |
| CHD3 | CHD4 | CHD5 | Chd7 |
| CHD8 | CHD9 | CHEK2 | CHRAC1 |
| CHRDL1 | |||
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