Cat.No.: | EAb-0182 |
Product Name: | PAR6A Polyclonal Antibody |
Product Overview: | Polyclonal antibody to detect endogenous levels of PAR6A in human samples |
Antibody Type: | Polyclonal |
Immunogen: | KLH-conjugated synthetic peptide of human PAR6A |
Host: | Rabbit |
Isotype: | IgG |
Antibody Target: | PARD6A |
Purification: | Affinity purified |
Appearance: | Colorless liquid |
Formulation: | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
Applications: | WB, IHC |
Recommended Dilutions/Conditions: |
WB; 1:500 – 1:2000, IH; 1:50 – 1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Positive Control: | WB: HT29; Jrukat; Raji; mouse testis; whole cell lysates; IHC: Rat kidney tissue |
Species Reactivity: | Human |
Shipping: | Gel Pack |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Q9NPB6 |
Alternative Name: | PAR6A; Partitioning defective 6 homolog alpha; PAR-6; PAR-6 alpha; PAR-6A; PAR6C; Tax interaction protein 40; TIP-40 |
Scientific Background: | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization. |
Product Types | ||
◆ Antibodies | ||
EAb-0059 | PARP Monoclonal Antibody | Inquiry |
EAb-0061 | PARP Polyclonal Antibody | Inquiry |
EAb-0062 | PARP (Cleaved) Polyclonal Antibody | Inquiry |
EAb-0063 | PARP (Cleaved) Polyclonal Antibody | Inquiry |
EAb-0064 | Paf1 Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
PABPC1L2A | PABPC5 | PABPN1 | PAD |
PAD1 | PAD2 | PAD3 | PAD4 |
PADI1 | PADI2 | PADI3 | PADI4 |
PADI6 | PAF1 | PAN2 | PAPD1 |
PAPD4 | PAPD5 | PAPD7 | PAPOLA More > |
PAPOLB | PARD6A | PARG | PARK2 |
PARK7 | PARP | PARP1 | PARP10 |
PARP11 | PARP12 | PARP14 | PARP15 |
PARP16 | PARP2 | PARP3 | PARP4 |
PARP6 | PARP7 | PARP8 | PARP9 |
PAX5 | PAX6 | PAX7 | PAX9 |
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