| Cat.No.: | EAb-0172 |
| Product Name: | USP37 Polyclonal Antibody |
| Product Overview: | Polyclonal antibody to detect endogenous levels of USP in human, mouse and rat. |
| Antibody Type: | Polyclonal |
| Immunogen: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human USP37 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | USP37 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Applications: | WB |
| Recommended Dilutions/Conditions: |
WB; 1:500 – 1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | WB: HeLa, mouse brain, rat brain lystes |
| Species Reactivity: | Human, Mouse, Rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q86T82 |
| Alternative Name: | KIAA1594, Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37 |
| Scientific Background: | Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0006 | USP3 Polyclonal Antibody | Inquiry |
| EAb-0007 | USP25 Polyclonal Antibody | Inquiry |
| EAb-0008 | USP2 Polyclonal Antibody | Inquiry |
| EAb-0009 | USP1 Polyclonal Antibody | Inquiry |
| EAb-0010 | USP7 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| USF1 | USP1 | USP10 | USP11 |
| USP12 | USP13 | USP14 | USP15 |
| USP16 | USP17L11 | USP17L12 | USP17L13 |
| USP17L15 | USP17L17 | USP17L1P | USP17L2 |
| USP17L22 | USP17L28 | USP17L3 | USP17L5 More > |
| USP17L8 | USP18 | USP19 | USP2 |
| USP20 | USP21 | USP22 | USP24 |
| USP25 | USP26 | USP27X | USP28 |
| USP29 | USP3 | USP30 | USP31 |
| USP32 | USP33 | USP34 | USP35 |
| USP36 | USP37 | USP38 | USP40 |
| USP42 | USP43 | USP44 | USP45 |
| USP46 | USP47 | USP48 | USP49 |
| USP5 | USP53 | USP54 | USP6 |
| USP6NL | USP7 | USP8 | USP9X |
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