| Cat.No.: | EAb-0150 |
| Product Name: | CBX2 Polyclonal Antibody |
| Product Overview: | Polyclonal Antibody to detect CBX2 in mouse samples. |
| Antibody Type: | Polyclonal |
| Immunogen: | Polyclonal antibody raised in rabbit against mouse CBX2 (chromobox homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein. |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | CBX2 |
| Purification: | Whole Anti-Sera |
| Appearance: | Colorless liquid |
| Formulation: | In PBS with 0.05% (W/V) sodium azide. |
| Applications: | ELISA. |
| Recommended Dilutions/Conditions: |
ELISA: 1:300. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | ELISA: Peptides. |
| Species Reactivity: | Mouse |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q14781 |
| Alternative Name: | CDCA6, M33, SRXY5 |
| Scientific Background: | CBX2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodelling and modification of histones; it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. CBX2 also is involved in sexual development, acting as an activator of NR5A1 expression. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0053 | Human CBX5 Knockout Cell Line 2bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0146 | CBX5 Polyclonal Antibody | Inquiry |
| EAb-0148 | CBX3 Polyclonal Antibody | Inquiry |
| EAb-0150 | CBX2 Polyclonal Antibody | Inquiry |
| EAb-0153 | CBFb Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| CBFb | CBX2 | CBX3 | CBX4 |
| CBX5 | CBX6 | CBX7 | CBX8 |
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