| Cat.No.: | EAb-0084 |
| Product Name: | HMG2L1 Polyclonal Antibody |
| Product Overview: | Polyclonal Antibody to detect HMG2L1 in human samples. |
| Antibody Type: | Polyclonal |
| Immunogen: | Polyclonal antibody raised in rabbit against human HMG2L1 (High mobility group protein 2-like 1) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and central region of the protein, respectively. |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | HMG2L1 |
| Purification: | Whole Anti-Sera |
| Appearance: | Colorless liquid |
| Formulation: | In PBS with 0.05% (W/V) sodium azide. |
| Applications: | ELISA. |
| Recommended Dilutions/Conditions: |
ELISA: 1:1000. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | ELISA: Peptides. |
| Species Reactivity: | Human |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9UGU5 |
| Alternative Name: | HMGXB4 |
| Scientific Background: | High mobility group (HMG) protein 1 and 2 has been classified by DNA binding preferences and are ubiquitous non-histone components of chromatin. They bind to the minor groove of AT-rich DNA sequences with high affinity. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFkB family, ATF-2 and c-Jun to activate transcription. HMG-2L1 (High mobility group protein 2-like 1), also known as HMGBCG, is a member of the HMG chromosomal protein superfamily. It contains a single HMG box DNA binding domain, and therefore does not contain an acidic C-terminal tail. HMG-2L1 is expressed in the nucleus and may play a role in transcriptional regulation. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0084 | HMG2L1 Polyclonal Antibody | Inquiry |
| EAb-0293 | HMGB4 Polyclonal Antibody | Inquiry |
| EAb-0309 | HMGB3 Polyclonal Antibody | Inquiry |
| EAb-0329 | HMGB1 Polyclonal Antibody | Inquiry |
| EAb-0333 | HMGB1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| HMG-1 | HMG2L1 | HMG4 | HMGA1 |
| HMGA2 | HMGB1 | HMGB2 | HMGB3 |
| HMGB4 | HMGN1 | HMGN2 | HMGN3 |
| HMGN5 | HMT1 | ||
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