| Cat.No.: | EAb-0070 |
| Product Name: | L3MBTL1 Polyclonal Antibody |
| Product Overview: | Polyclonal Antibody to detect L3MBTL1 in human samples. |
| Antibody Type: | Polyclonal |
| Immunogen: | Polyclonal antibody raised in rabbit against human L3MBTL1 (lethal 3 malignant brain tumor-like protein), using the N-terminal part of the protein. |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | L3MBTL1 |
| Purification: | Protein G purified |
| Appearance: | Colorless liquid |
| Formulation: | In PBS with 0.05% sodium azide and 0.05% ProClin 300. |
| Applications: | Western blot, IP. |
| Recommended Dilutions/Conditions: |
Western Blot: 1:1000, IP: 1 - 5 µg/IP Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Western blot: HeLa cells, IP: HeLa cells |
| Species Reactivity: | Human |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9Y468 |
| Alternative Name: | L3MBTL, L3MBT |
| Scientific Background: | L3MBTL1 is a member of the polycomb group (PcG) proteins, which function as transcriptional regulators in large protein complexes. In Drosophila, homozygous mutations in the L3MBTL1 gene have been demonstrated to cause brain tumors, identifying L3MBTL1 as a tumor suppressor gene. L3MBTL1 forms a homodimer and interacts with TEL (ETV6). L3MBTL1 probably plays a role in cell proliferation. Overexpression of L3MBTL1 induces multinucleated cells, suggesting that it is required for normal mitosis. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0070 | L3MBTL1 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0077 | Recombinant Human L3MBTL1 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0097 | Human L3MBTL2 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0244 | UNC 1215 | Inquiry |
| BSM-0245 | UNC-669 | Inquiry |
| Related Gene / Proteins | |||
| L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 |
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