| Cat.No.: | EAb-0053 |
| Product Name: | PIM1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide surrounding amino acid 296 of rat PIM1 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | PIM1 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | 100 µg (0.5 mg/ml) affinity purified rabbit anti-PIM1 polyclonal antibody in phosphate (PBS, pH 7.2) containing 30% glycerol, 0.5 % BSA and 0.01% thimerosal. |
| Applications: | Western blot |
| Recommended Dilutions/Conditions: |
Western blot analysis (0.5-4 µg/ml). Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, mouse, rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P26794 |
| Scientific Background: | The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved throμgh evolution in multicellular organisms. Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Recently, Pim1 has been shown to enhance the activities of p100, c-Myb and Cdc 25a and in part this might explain reported effects of Pim1 on mitogenesis. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0053 | PIM1 Polyclonal Antibody | Inquiry |
| EAb-0326 | PIM1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0200 | Quercetin, Dihydrate | Inquiry |
| BSM-0223 | SMI-4a | Inquiry |
| BSM-0271 | CUDC-907 | Inquiry |
| Related Gene / Proteins | |||
| PI3K | PIAS2 | PIAS4 | PIASy |
| PID | PIM | PIM1 | PIM1 |
| PIM2 | PITX2 | PiwiL2 | PIWIL4 |
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