Cat.No.: | EAb-0032 |
Product Name: | Setd1a Polyclonal Antibody |
Product Overview: | Polyclonal Antibody to detect Setd1a in mouse samples. |
Antibody Type: | Polyclonal |
Immunogen: | Polyclonal antibody raised in rabbit against mouse Setd1a (Set domain containing 1A), using three KLH-conjugated synthetic peptides: two containing an amino acid sequence from the N-terminal part of the protein and one containing an amino acid sequence fr |
Host: | Rabbit |
Isotype: | IgG |
Antibody Target: | Setd1a |
Purification: | Whole Anti-Sera |
Appearance: | Colorless liquid |
Formulation: | In PBS with 0.05% (W/V) sodium azide. |
Applications: | Western blot, ELISA. |
Recommended Dilutions/Conditions: |
ELISA: 1:100, Western Blot: 1:500. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Positive Control: | Western blot: NIH3T3 and embryonic stem cells, ELISA: Peptides. |
Species Reactivity: | Mouse |
Shipping: | Gel Pack |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | O15047 |
Alternative Name: | SET1, SET1A, KMT2F |
Scientific Background: | SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
◆ Antibodies | ||
EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
SENP3 | SENP8 | SET | SET1 |
SET2 | SET7 | SET8 | SET9 |
SETBP1 | SETD1A | SETD1B | SETD2 |
SETD3 | SETD5 | SETD6 | SETD7 |
SETD8 | SETD9 | SetDB1 | SETDB2 More > |
SETMAR |
USA
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