| Cat.No.: | EAb-0016 |
| Product Name: | TDRD4 Polyclonal Antibody |
| Product Overview: | Polyclonal Antibody to detect TDRD4 in human samples |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant human TDRD4 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | TDRD4 |
| Purification: | Affinity Purified Antibody |
| Appearance: | Colorless liquid |
| Formulation: | 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol. |
| Applications: | Western blot |
| Recommended Dilutions/Conditions: |
Western blot: 1-4 µg/ml. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Western Blot: Recombinant protein |
| Species Reactivity: | Human |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9BXT8 |
| Alternative Name: | RING finger protein 17, Tudor domain-containing protein 4, TDRD4, RNF17 |
| Scientific Background: | Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The Tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The Tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. TDRD4 is a candidate CT antigen expressed in a subset of liver cancers |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0016 | TDRD4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0049 | Recombinant Human TDRD3 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0285 | Human TDG Knockout Cell Line 2bp insertion | Inquiry |
| CL-0286 | Human TDGF1 Knockout Cell Line | Inquiry |
| CL-0431 | Human TDP1 Knockout Cell Line 13bp deletion | Inquiry |
| Related Gene / Proteins | |||
| TDF | TDG | TDGF1 | TDP1 |
| TDRD12 | TDRD3 | TDRD4 | TDRD4 |
| TDT | |||
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