| Cat.No.: | EL-0064 |
| Product Name: | Recombinant Human SMARCB1 Cell Lysate |
| Description: | The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. |
| Species: | Human |
| Warning: | For research use only, not for diagnostic or therapeutic use. |
| Gene ID NCBI: | 6598 |
| Official Symbol: | SMARCB1 |
| Official Full Name: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| Synonyms: | SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SNF5L1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; BAF47; hSNFS; Ini1; integrase interactor 1; malignant rhabdoid tumor suppressor; RDT; Sfh1p; Snr1; sucrose nonfermenting; yeast; homolog like 1; hSNF5; SNF5 homolog; BRG1-associated factor 47; integrase interactor 1 protein; sucrose nonfermenting, yeast, homolog-like 1; INI1; SNF5; RTPS1; |
| mRNA Refseq: | NM_001007468 |
| Protein Refseq: | NP_001007469 |
| MIM: | 601607 |
| UniProt ID: | Q12824 |
| Chromosome Location: | 22q11.23 |
| Function: | Tat protein binding; p53 binding; protein binding; transcription coactivator activity; transcription coactivator activity; |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
| EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
| SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
| SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
| SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
| SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
| SMCX | SMN | SMN1 | SMN2 |
| SMOC2 | SMRT | SMT3 | SMUG1 |
| SMURF2 | SMYD1 | SMYD2 | SMYD2B |
| SMYD3 | SMYD4 | SMYD5 | |
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