| Cat.No.: | BSM-0362 |
| Product Name: | PCNA-I1 |
| CAS No.: | 444930-42-1 |
| Figure: |
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| Product Overview: | An inhibitor of PCNA |
| Description: | PCNA-I1 is an inhibitor of proliferating cell nuclear antigen (PCNA) that binds to PCNA trimers (Kd = 0.41 µM) and dose-dependently reduces the level of PCNA associated with chromatin in PC3 cells. It preferentially inhibits growth of a variety of human and mouse cancer cell lines (IC50s = 0.05-0.3 µM) over non-transformed cells (IC50s = 0.99-2 µM). |
| Appearance: | A crystalline solid |
| Molecular Weight: | 310.4 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | PCNA |
| Molecular Formula: | C17H14N2O2S |
| Chemical Name: | 3-methyl-2-[(1-hydroxy-2-naphthalenyl)methylene]hydrazide-2-thiophenecarboxylic acid |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0039 | Embelin | Inquiry |
| BSM-0108 | Curcumin, Curcuma longa (High Purity) | Inquiry |
| BSM-0133 | Garcinol | Inquiry |
| ◆ Antibodies | ||
| EAb-0060 | PCAF Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0106 | Recombinant Human PCNA Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| PCAF | PCBP2 | PCBP3 | PCBP4 |
| PCGF2 | PCGF6 | PCL2 | PCNA |
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