| Cat.No.: | BSM-0335 |
| Product Name: | MM-102 |
| CAS No.: | 1417329-24-8 |
| Figure: |
|
| Product Overview: | An inhibitor of WDR5/MLL interactions |
| Description: | MM-102 is a potent WDR5/MLL interaction inhibitor (IC50 = 2.4 nM). It has been shown to block MLL1 methyltransferase activity, reducing the expression of HoxA9 and Meis-1 genes, which are both critical MLL1 target genes in MLL1 fusion protein-mediated leukemogenesis. MM-102 can also inhibit cell growth and induce apoptosis in leukemia cells harboring MLL1 fusion proteins. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 669.8 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | WDR5/MLL interactions |
| Molecular Formula: | C35H49F2N7O4 |
| Chemical Name: | 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0005 | WDR5 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0052 | Recombinant Human WDTC1 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0170 | MI-3 | Inquiry |
| BSM-0187 | OICR-9429 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0172 | Human KMT2C / MLL3 peptide | Inquiry |
| Related Gene / Proteins | |||
| MLH1 | MLL | mll1 | MLL2 |
| MLL3 | MLL4 | MLL5 | MLLT1 |
| MLLT3 | WDHD1 | WDR4 | WDR5 |
| WDR77 | WDR82 | WDTC1 | |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
