| Cat.No.: | BSM-0311 |
| Product Name: | LMK 235 |
| CAS No.: | 1418033-25-6 |
| Figure: |
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| Product Overview: | A selective inhibitor of HDAC4 and HDAC5 |
| Description: | LMK 235 is an HDAC inhibitor that selectively targets HDACs 4 and 5 (IC50s = 12 and 4 nM, respectively) over other HDACs (IC50s = 56, 320, 850, 880, and 1,280 for HDACs 6, 1, 11, 2, and 8, respectively). It displays enhanced cytotoxic effects against human cancer cell lines, compared to SAHA or trichostatin A. LMK 235 and derivatives inhibit the growth of the malarial parasite P. falciparum at multiple life cycle stages at nanomolar concentrations. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 294.4 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | HDAC4; HDAC5 |
| Molecular Formula: | C15H22N2O4 |
| Chemical Name: | N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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