| Cat.No.: | BSM-0293 |
| Product Name: | BRD9539 |
| CAS No.: | 1374601-41-8 |
| Figure: |
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| Product Overview: | An inhibitor of EHMT2/G9a and PRC2 in enzyme assays |
| Description: | BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 µM. It inhibits polycomb repressive complex 2 (PRC2) to a similar extent with 54 and 43% activity remaining for G9a and PRC2, respectively, when used at a concentration of 10 µM. It is selective for G9a and PRC2 over SU39H1 and NDMT1 up to a concentration of 40 µM. It is more potent than BRD4770 in enzyme assays but has no activity in cell-based assays when used at concentrations of 5 and 10 µM. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 399.4 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | EHMT2/G9a; PRC2 |
| Molecular Formula: | C24H21N3O3 |
| Chemical Name: | 2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0025 | BIX01294 (hydrochloride hydrate) | Inquiry |
| BSM-0026 | UNC0224 | Inquiry |
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| EHD2 | EHMT1 | EHMT2 | Pr-SET7 |
| PRC1 | PRC2 | PRDM1 | PRDM10 |
| PRDM11 | PRDM12 | PRDM13 | PRDM14 |
| PRDM15 | PRDM16 | PRDM17 | PRDM2 |
| PRDM3 | PRDM4 | PRDM5 | PRDM6 More > |
| PRDM7 | PRDM8 | PRDM9 | PREP1 |
| PRIM2 | PRKAA2 | PRKCA | PRKCB |
| PRKCE | PRKDC | PRKRIP1 | PRMT |
| prmt1 | PRMT2 | PRMT3 | PRMT5 |
| prmt6 | PRMT7 | PRMT8 | PRMT9 |
| Progerin | Protamine 2 | Prox1 | PRPF31 |
| PRPF40A | PRSS12 | PRSS55 | PRTFDC1 |
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