| Cat.No.: | BSM-0228 |
| Product Name: | Splitomicin |
| CAS No.: | 5690-03-9 |
| Figure: |
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| Synonyms: | Splitomycin, 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one |
| Description: | Initially shown to inhibit Sir2p (the yeast Sirt1 homolog) and create a conditional phenocopy of a sir2 deletion mutant in S. cerevisiae. Acts by either altering or blocking access to the acetylated histone binding pocket. |
| Appearance: | White to off-white solid |
| Molecular Weight: | 198.2 |
| Purity: | ≥98% |
| Storage: | 4°C |
| Targets: | Sir2p (yeast Sirt1 homolog) |
| Molecular Formula: | C13H10O2 |
| MDL Number: | MFCD08705254 |
| Solubility: | DMSO (100 mg/ml) |
| Shipping Conditions: | RT |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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